What are sensitizers known to cause in the body?

Sensitizers are substances that can cause an allergic reaction in some individuals after repeated exposure. When a sensitizer comes into contact with the skin or is inhaled, it may trigger an immune response in the body, leading to symptoms such as rashes, respiratory issues, or other allergic reactions. The key characteristic of sensitizers is that, unlike irritants that produce immediate effects, sensitizers often require prior exposure to develop sensitivity.

Once an individual has been sensitized, even minimal subsequent exposure can trigger allergic reactions. These reactions can manifest in various ways, including skin irritation or respiratory problems, but the defining aspect is that they stem from the immune system's response to the sensitizing agent.

Other choices represent different types of effects or reactions that substances can cause, but they don't specifically relate to the unique mechanism of sensitizers. For instance, while some chemicals may cause burns or respiratory issues, those are not defining characteristics of sensitizers. Sensory overload refers to an overwhelming response to stimuli and is not linked to the allergic mechanisms associated with sensitizers. Hence, allergic reactions are indeed the hallmark outcome of exposure to sensitizers.