Which part of the body is most likely to be damaged by carbon tetrachloride?

The liver is the organ most likely to be damaged by carbon tetrachloride due to its role in metabolizing toxic substances. Carbon tetrachloride is a solvent that, upon entering the body, undergoes metabolic activation primarily in the liver. The reactive metabolites formed during this process can lead to cellular injury and necrosis in liver tissue. The liver is particularly vulnerable because it filters blood from the digestive tract, where carbon tetrachloride may be absorbed, and it is responsible for detoxifying various substances.

Liver damage can manifest in a variety of ways, including fatty liver changes, hepatitis, or even liver failure in severe cases. Because carbon tetrachloride is a known hepatotoxic compound, the liver's capacity to process it is overwhelmed, resulting in significant oxidative stress and liver cell damage.

Understanding the specific health impacts of carbon tetrachloride is crucial for implementing effective safety measures and ensuring proper handling to minimize exposure risks in occupational settings.